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Basis for ligand discrimination between ON and OFF state riboswitch conformations: The case of the SAM-I riboswitch
Riboswitches are RNA elements that bind to effector ligands and control gene expression. Most consist of two domains. S-Adenosyl Methionine (SAM) binds the aptamer domain of the SAM-I riboswitch and induces conformational changes in the expression domain to form an intrinsic terminator (transcriptio...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358645/ https://ncbi.nlm.nih.gov/pubmed/22543867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.032177.111 |
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