Role of CD25(+) dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis (EAU)

In the present study, we showed that in vivo administration of an anti-CD25 antibody (PC61) decreased the Th17 response in C57BL/6 (B6) mice immunized with the uveitogenic peptide IRBP(1–20), while enhancing the autoreactive Th1 response. The depressed Th17 response was closely associated with decre...

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Main Authors: Liang, Dongchun, Zuo, Aijun, Shao, Hui, Born, Willi K., O'Brien, Rebecca L., Kaplan, Henry J., Sun, Deming
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358586/
https://ncbi.nlm.nih.gov/pubmed/22539790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200109
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