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Role of CD25(+) dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis (EAU)
In the present study, we showed that in vivo administration of an anti-CD25 antibody (PC61) decreased the Th17 response in C57BL/6 (B6) mice immunized with the uveitogenic peptide IRBP(1–20), while enhancing the autoreactive Th1 response. The depressed Th17 response was closely associated with decre...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358586/ https://ncbi.nlm.nih.gov/pubmed/22539790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200109 |
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