Infliximab Exerts No Direct Hepatotoxic Effect on HepG2 Cells In Vitro

BACKGROUND: Infliximab-induced hepatotoxicity is reported in several case studies involving patients with inflammatory bowel disease (IBD) and a direct hepatotoxic effect has been proposed. OBJECTIVE: The aim of this study was to determine the direct in vitro toxicity of infliximab. As a proof of pr...

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Autori principali: de Vries, Hilbert S., de Heij, Tineke, Roelofs, Henie M. J., te Morsche, Rene H. M., Peters, Wilbert H. M., de Jong, Dirk J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2012
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358583/
https://ncbi.nlm.nih.gov/pubmed/22535279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-012-2159-7
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