Stem cell factor programs the mast cell activation phenotype

Mast cells, activated by antigen via the high affinity receptor for IgE (FcεRI), release an array of pro-inflammatory mediators that contribute to allergic disorders such as asthma and anaphylaxis. The KIT ligand, stem cell factor (SCF), is critical for mast cell expansion, differentiation and survi...

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Auteurs principaux: Ito, Tomonobu, Smrz, Daniel, Jung, Mi-Yeon, Bandara, Geethani, Desai, Avanti, Smrzová, Sárka, Kuehn, Hye Sun, Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358494/
https://ncbi.nlm.nih.gov/pubmed/22529299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103366
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