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Stepwise Molecular Display Utilizing Icosahedral and Helical Complexes of Phage Coat and Decoration Proteins in the Development of Robust Nanoscale Display Vehicles

A stepwise addition protocol was developed to display cargo using bacteriophage P22 capsids and the phage decorator (Dec) protein. Three-dimensional image reconstructions of frozen-hydrated samples of P22 particles with nanogold-labeled Dec bound to them revealed the locations of the N- and C- termi...

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Autors principals: Parent, Kristin N., Deedas, Christina T., Egelman, Edward H., Casjens, Sherwood R., Baker, Timothy S., Teschke, Carolyn M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358469/
https://ncbi.nlm.nih.gov/pubmed/22575828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.04.026
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