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β-catenin stabilization in skeletal muscles, but not in motor neurons, leads to aberrant motor innervation of the muscle during neuromuscular development in mice

β-catenin, a key component of the Wnt signaling pathway, has been implicated in the development of the neuromuscular junction (NMJ) in mice, but its precise role in this process remains unclear. Here we use a β-catenin gain-of-function mouse model to stabilize β-catenin selectively in either skeleta...

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Detalhes bibliográficos
Main Authors: Liu, Yun, Sugiura, Yoshie, Wu, Fenfen, Mi, Wentao, Taketo, Makoto M., Cannon, Steve, Carroll, Thomas, Lin, Weichun
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358465/
https://ncbi.nlm.nih.gov/pubmed/22537499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.04.003
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