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β-catenin stabilization in skeletal muscles, but not in motor neurons, leads to aberrant motor innervation of the muscle during neuromuscular development in mice

β-catenin, a key component of the Wnt signaling pathway, has been implicated in the development of the neuromuscular junction (NMJ) in mice, but its precise role in this process remains unclear. Here we use a β-catenin gain-of-function mouse model to stabilize β-catenin selectively in either skeleta...

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Autors principals: Liu, Yun, Sugiura, Yoshie, Wu, Fenfen, Mi, Wentao, Taketo, Makoto M., Cannon, Steve, Carroll, Thomas, Lin, Weichun
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358465/
https://ncbi.nlm.nih.gov/pubmed/22537499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.04.003
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