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Stathmin regulates microtubule dynamics and MTOC polarization in activated T cells

Polarization of T cells involves reorientation of the microtubule-organizing center (MTOC). Because activated ERK is localized at the immunological synapse, we investigated its role by showing that ERK activation is important for MTOC polarization. Suspecting that ERK phosphorylates a regulator of m...

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Détails bibliographiques
Auteurs principaux: Filbert, Erin L., Le Borgne, Marie, Lin, Joseph, Heuser, John E., Shaw, Andrey S.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358357/
https://ncbi.nlm.nih.gov/pubmed/22529300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200242
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