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Stathmin regulates microtubule dynamics and MTOC polarization in activated T cells

Polarization of T cells involves reorientation of the microtubule-organizing center (MTOC). Because activated ERK is localized at the immunological synapse, we investigated its role by showing that ERK activation is important for MTOC polarization. Suspecting that ERK phosphorylates a regulator of m...

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Autori principali: Filbert, Erin L., Le Borgne, Marie, Lin, Joseph, Heuser, John E., Shaw, Andrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358357/
https://ncbi.nlm.nih.gov/pubmed/22529300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200242
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