Therapeutic Dosing of Acenocoumarol: Proposal of a Population Specific Pharmacogenetic Dosing Algorithm and Its Validation in North Indians

OBJECTIVES: To develop a population specific pharmacogenetic acenocoumarol dosing algorithm for north Indian patients and show its efficiency in dosage prediction. METHODS: Multiple and linear stepwise regression analyses were used to include age, sex, height, weight, body surface area, smoking stat...

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Main Authors: Rathore, Saurabh Singh, Agarwal, Surendra Kumar, Pande, Shantanu, Singh, Sushil Kumar, Mittal, Tulika, Mittal, Balraj
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358293/
https://ncbi.nlm.nih.gov/pubmed/22629463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037844
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