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Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage

Cytochrome P450-C17 enzyme (CYP17) is an important component of the androgen synthesis pathway, a pathway that is dysfunctional in polycystic ovary syndrome (PCOS). Variation in 11-beta hydroxysteroid dehydrogenase (HSD11B1) is associated with cortisone reductase deficiency, a condition with a pheno...

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Detalhes bibliográficos
Main Authors: Chua, Angela K., Azziz, Ricardo, Goodarzi, Mark O.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358039/
https://ncbi.nlm.nih.gov/pubmed/22238371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gas002
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