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Association of CYP3A7*1C and Serum Dehydroepiandrosterone Sulfate Levels in Women with Polycystic Ovary Syndrome

Context: Adrenal androgen excess is common in polycystic ovary syndrome (PCOS) and appears to be heritable. CYP3A7 metabolizes dehydroepiandrosterone and its sulfate (DHEAS). A promoter variant, CYP3A7*1C, which results in persistent expression in adults, was associated with reduced DHEAS levels in...

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Detalhes bibliográficos
Main Authors: Goodarzi, Mark O., Xu, Ning, Azziz, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453058/
https://ncbi.nlm.nih.gov/pubmed/18445661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-0403
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