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Cellular retinoic acid-binding proteins are essential for hindbrain patterning and signal robustness in zebrafish

The vitamin A derivative retinoic acid (RA) is a morphogen that patterns the anterior-posterior axis of the vertebrate hindbrain. Cellular retinoic acid-binding proteins (Crabps) transport RA within cells to both its nuclear receptors (RARs) and degrading enzymes (Cyp26s). However, mice lacking Crab...

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Hlavní autoři: Cai, Anna Q., Radtke, Kelly, Linville, Angela, Lander, Arthur D., Nie, Qing, Schilling, Thomas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357909/
https://ncbi.nlm.nih.gov/pubmed/22619388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.077065
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