Staurosporine Inhibits Frequency-Dependent Myofilament Desensitization in Intact Rabbit Cardiac Trabeculae

Myofilament calcium sensitivity decreases with frequency in intact healthy rabbit trabeculae and associates with Troponin I and Myosin light chain-2 phosphorylation. We here tested whether serine-threonine kinase activity is primarily responsible for this frequency-dependent modulations of myofilame...

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Detalhes bibliográficos
Main Authors: Varian, Kenneth D., Biesiadecki, Brandon J., Ziolo, Mark T., Davis, Jonathan P., Janssen, Paul M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357507/
https://ncbi.nlm.nih.gov/pubmed/22649731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/290971
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