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Homozygosity Mapping on a Single Patient—Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data
Homozygosity mapping has played an important role in detecting recessive mutations using families of consanguineous marriages. However, detection of regions identical and homozygosity by descent (HBD) when family data are not available, or when relationships are unknown, is still a challenge. Making...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357498/ https://ncbi.nlm.nih.gov/pubmed/21309031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21432 |
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