Pitfalls in Homozygosity Mapping

There is much interest in use of identity-by-descent (IBD) methods to map genes, both in Mendelian and in complex disorders. Homozygosity mapping provides a rapid means of mapping autosomal recessive genes in consanguineous families by identifying chromosomal regions that show homozygous IBD segment...

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Detalhes bibliográficos
Main Authors: Miano, Maria G., Jacobson, Samuel G., Carothers, Andrew, Hanson, Isabel, Teague, Peter, Lovell, Jill, Cideciyan, Artur V., Haider, Neena, Stone, Edwin M., Sheffield, Val C., Wright, Alan F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288578/
https://ncbi.nlm.nih.gov/pubmed/11007652
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