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Conserved Orb6 Phosphorylation Sites Are Essential for Polarized Cell Growth in Schizosaccharomyces pombe

The Ndr-related Orb6 kinase is a key regulator of polarized cell growth in fission yeast, however the mechanism of Orb6 activation is unclear. Activation of other Ndr kinases involves both autophosphorylation and phosphorylation by an upstream kinase. Previous reports suggest that the Nak1 kinase fu...

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Bibliographic Details
Main Authors: Liu, Guohong, Young, Dallan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357421/
https://ncbi.nlm.nih.gov/pubmed/22629372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037221
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