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btn1 Affects Endocytosis, Polarization of Sterol-Rich Membrane Domains and Polarized Growth in Schizosaccharomyces pombe

btn1, the Schizosaccharomyces pombe orthologue of the human Batten disease gene CLN3, exerts multiple cellular effects. As well as a role in vacuole pH homoeostasis, we now show that Btn1p is essential for growth at high temperatures. Its absence results in progressive defects at 37°C that culminate...

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Autori principali: Codlin, Sandra, Haines, Rebecca L, Mole, Sara E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440566/
https://ncbi.nlm.nih.gov/pubmed/18346214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2008.00735.x
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