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S. pombe btn1, the orthologue of the Batten disease gene CLN3, is required for vacuole protein sorting of Cpy1p and Golgi exit of Vps10p

Batten disease is characterised by lysosomal dysfunction. The most common type of the disease is caused by mutations in the membrane protein CLN3, whose function is unknown. We show that the fission yeast orthologue Btn1p, previously implicated in vacuole function, is required for correct sorting of...

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Sonraí Bibleagrafaíochta
Main Authors: Codlin, Sandra, Mole, Sara E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Company of Biologists 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714440/
https://ncbi.nlm.nih.gov/pubmed/19299465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.038323
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