Scanometric microRNA (Scano-miR) Array Profiling of Prostate Cancer Markers Using Spherical Nucleic Acid (SNA)-Gold Nanoparticle Conjugates

We report the development of a novel Scanometric MicroRNA (Scano-miR) platform for the detection of relatively low abundance miRNAs with high specificity and reproducibility. The Scano-miR system was able to detect 1 fM concentrations of miRNA in serum with single nucleotide mismatch specificity. In...

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Bibliographic Details
Main Authors: Alhasan, Ali H., Kim, Dae Y., Daniel, Weston L., Watson, Erin, Meeks, Joshua J., Thaxton, C. Shad, Mirkin, Chad A.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357313/
https://ncbi.nlm.nih.gov/pubmed/22489825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3004055
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