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Enhanced Attenuation of Nicotine Discrimination in Rats by Combining Nicotine-Specific Antibodies with a Nicotinic Receptor Antagonist
Tobacco addiction requires activation by nicotine of a variety of central nicotinic acetylcholine receptors (nAChRs). In animals, both nAChR antagonists and immunization against nicotine can reduce nAChR activation by nicotine and block a variety of addiction-relevant behaviors. However, clinical us...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357089/ https://ncbi.nlm.nih.gov/pubmed/22503967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2012.03.026 |
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