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Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol
The two main groups of antidepressant drugs, the tricyclic antidepressants (TCAs) and the selective serotonin reuptake inhibitors (SSRIs), as well as several other compounds, act by inhibiting the serotonin transporter (SERT). However, the binding mode and molecular mechanism of inhibition in SERT a...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357065/ https://ncbi.nlm.nih.gov/pubmed/22071255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.09.056 |
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