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Chemical Inhibition of Bacterial Protein Tyrosine Phosphatase Suppresses Capsule Production
Capsule polysaccharide is a major virulence factor for a wide range of bacterial pathogens, including Streptococcus pneumoniae. The biosynthesis of Wzy-dependent capsules in both Gram-negative and –positive bacteria is regulated by a system involving a protein tyrosine phosphatase (PTP) and a protei...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356977/ https://ncbi.nlm.nih.gov/pubmed/22629313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036312 |
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