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Dendritic BDNF Synthesis Is Required for Late-Phase Spine Maturation and Recovery of Cortical Responses Following Sensory Deprivation

Sensory experience in early postnatal life shapes neuronal connections in the brain. Here we report that the local synthesis of brain-derived neurotrophic factor (BDNF) in dendrites plays an important role in this process. We found that dendritic spines of layer 2/3 pyramidal neurons of the visual c...

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Detalhes bibliográficos
Main Authors: Kaneko, Megumi, Xie, Yuxiang, An, Juan Ji, Stryker, Michael P., Xu, Baoji
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356781/
https://ncbi.nlm.nih.gov/pubmed/22492034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4462-11.2012
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