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Dendritic BDNF Synthesis Is Required for Late-Phase Spine Maturation and Recovery of Cortical Responses Following Sensory Deprivation

Sensory experience in early postnatal life shapes neuronal connections in the brain. Here we report that the local synthesis of brain-derived neurotrophic factor (BDNF) in dendrites plays an important role in this process. We found that dendritic spines of layer 2/3 pyramidal neurons of the visual c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kaneko, Megumi, Xie, Yuxiang, An, Juan Ji, Stryker, Michael P., Xu, Baoji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356781/
https://ncbi.nlm.nih.gov/pubmed/22492034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4462-11.2012
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