Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT—Part II: Physiologically Based Pharmacokinetic Modeling and Manganese Risk Assessment

Recently, a variety of physiologically based pharmacokinetic (PBPK) models have been developed for the essential element manganese. This paper reviews the development of PBPK models (e.g., adult, pregnant, lactating, and neonatal rats, nonhuman primates, and adult, pregnant, lactating, and neonatal...

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Détails bibliographiques
Auteurs principaux: Taylor, Michael D., Clewell, Harvey J., Andersen, Melvin E., Schroeter, Jeffry D., Yoon, Miyoung, Keene, Athena M., Dorman, David C.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356703/
https://ncbi.nlm.nih.gov/pubmed/22645610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/791431
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