MicroRNAs miR-125a and miR-125b constitutively activate the NF-κB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)

Constitutive activation of the NF-κB pathway is associated with diffuse large B-cell lymphoma (DLBCL) pathogenesis, but whether microRNA dysfunction can contribute to these events remains unclear. Starting from an integrative screening strategy, we uncovered that the negative NF-κB regulator TNFAIP3...

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Detalles Bibliográficos
Main Authors: Kim, Sang-Woo, Ramasamy, Kumaraguruparan, Bouamar, Hakim, Lin, An-Ping, Jiang, Daifeng, Aguiar, Ricardo C. T.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356650/
https://ncbi.nlm.nih.gov/pubmed/22550173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200081109
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