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miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas

Diffusely infiltrating gliomas are among the most prognostically discouraging neoplasia in human. Temozolomide (TMZ) in combination with radiotherapy is currently used for the treatment of glioblastoma (GBM) patients, but less than half of the patients respond to therapy and chemoresistance develops...

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Foilsithe in:Cell Death Dis
Main Authors: Haemmig, S, Baumgartner, U, Glück, A, Zbinden, S, Tschan, M P, Kappeler, A, Mariani, L, Vajtai, I, Vassella, E
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611719/
https://ncbi.nlm.nih.gov/pubmed/24901050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.245
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