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FoxA family members are crucial regulators of the hypertrophic chondrocyte differentiation program

During endochondral ossification small immature chondrocytes enlarge to form hypertrophic chondrocytes, which express collagen X. In this work, we demonstrate that FoxA factors are induced during chondrogenesis, bind to conserved binding sites in the collagen X enhancer, and can promote the expressi...

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Detalhes bibliográficos
Main Authors: Ionescu, Andreia, Kozhemyakina, Elena, Nicolae, Claudia, Kaestner, Klaus H., Olsen, Bjorn R., Lassar, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356573/
https://ncbi.nlm.nih.gov/pubmed/22595668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.03.011
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