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CD91-dependent programming of T helper cell responses following Heat Shock Protein immunization
The immunogenic Heat shock proteins (HSPs) gp96, hsp70 and calreticulin bind to CD91 on antigen presenting cells for cross-presentation of the HSP-chaperoned peptides. This event leads to priming of T cell responses. We show that CD91 serves as a signaling receptor for these HSPs allowing for the ma...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356570/ https://ncbi.nlm.nih.gov/pubmed/22045000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1524 |
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