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CD91-dependent programming of T helper cell responses following Heat Shock Protein immunization

The immunogenic Heat shock proteins (HSPs) gp96, hsp70 and calreticulin bind to CD91 on antigen presenting cells for cross-presentation of the HSP-chaperoned peptides. This event leads to priming of T cell responses. We show that CD91 serves as a signaling receptor for these HSPs allowing for the ma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pawaria, Sudesh, Binder, Robert J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356570/
https://ncbi.nlm.nih.gov/pubmed/22045000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1524
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