Effectiveness of a Combination Therapy Using Calcineurin Inhibitor and mTOR Inhibitor in Preventing Allograft Rejection and Post-Transplantation Renal Cancer Progression

Calcineurin inhibitors (CNIs) may promote post-transplantation cancer through altered expression of cytokines and chemokines in tumor cells. We found that there is a potential cross-talk among CNI-induced signaling molecules and mTOR. Here, we utilized a murine model of post-transplantation cancer t...

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Hauptverfasser: Basu, Aninda, Liu, Tao, Banerjee, Pallavi, Flynn, Evelyn, Zurakowski, David, Datta, Dipak, Viklicky, Ondrej, Gasser, Martin, Waaga-Gasser, Ana Maria, Yang, Jun, Pal, Soumitro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356500/
https://ncbi.nlm.nih.gov/pubmed/22343319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.02.004
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