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Topological Domains in Mammalian Genomes Identified by Analysis of Chromatin Interactions
The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is coarse, fragmented and incomplete. In the nucleus of eukaryotic cells, interphase chromosomes occupy distinct chromosome territories (CT), and numerous m...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356448/ https://ncbi.nlm.nih.gov/pubmed/22495300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11082 |
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