A Dual Role for UVRAG in Maintaining Chromosomal Stability Independent of Autophagy

Autophagy defects have been recently associated with chromosomal instability (CIN), a hallmark of human cancer. However, the functional specificity and mechanism of action of autophagy-related factors in genome stability remain elusive. Here we report that UVRAG, an autophagic tumor suppressor, play...

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Detalhes bibliográficos
Main Authors: Zhao, Zhen, Oh, Soohwan, Li, Dapeng, Ni, Duojiao, Pirooz, Sara Dolatshahi, Lee, Joo-Hyung, Yang, Shunhua, Lee, June-Yong, Ghozalli, Irene, Costanzo, Vincenzo, Stark, Jeremy M., Liang, Chengyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356442/
https://ncbi.nlm.nih.gov/pubmed/22542840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.12.027
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