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Estrogen Upregulates Cyclic AMP Response Element Modulator α Expression and Downregulates Interleukin-2 Production by Human T Lymphocytes

Systemic lupus erythematosus (SLE) is an autoimmune disease with a complex multifactorial pathogenesis. T lymphocytes play a critical role in disease pathogenesis and display abnormal gene expression and poor interleukin (IL)-2 production. We previously showed that the expression of the transcriptio...

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Detalhes bibliográficos
Main Authors: Moulton, Vaishali R, Holcomb, Dana R, Zajdel, Melissa C, Tsokos, George C
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356426/
https://ncbi.nlm.nih.gov/pubmed/22281835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00506
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