α-Thalassemia Impairs the Cytoadherence of Plasmodium falciparum-Infected Erythrocytes

BACKGROUND: α-thalassemia results from decreased production of α-globin chains that make up part of hemoglobin tetramers (Hb; α(2)β(2)) and affects up to 50% of individuals in some regions of sub-Saharan Africa. Heterozygous (−α/αα) and homozygous (−α/−α) genotypes are associated with reduced risk o...

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Bibliographische Detailangaben
Hauptverfasser: Krause, Michael A., Diakite, Seidina A. S., Lopera-Mesa, Tatiana M., Amaratunga, Chanaki, Arie, Takayuki, Traore, Karim, Doumbia, Saibou, Konate, Drissa, Keefer, Jeffrey R., Diakite, Mahamadou, Fairhurst, Rick M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356384/
https://ncbi.nlm.nih.gov/pubmed/22623996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037214
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