Ex-Vivo Cytoadherence Phenotypes of Plasmodium falciparum Strains from Malian Children with Hemoglobins A, S, and C

Sickle hemoglobin (Hb) S and HbC may protect against malaria by reducing the expression of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) on the surface of parasitized red blood cells (RBCs), thereby weakening their cytoadherence to microvascular endothelial cells (MVECs) and impairin...

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Hauptverfasser: Beaudry, Jeanette T., Krause, Michael A., Diakite, Seidina A. S., Fay, Michael P., Joshi, Gyan, Diakite, Mahamadou, White, Nicholas J., Fairhurst, Rick M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960211/
https://ncbi.nlm.nih.gov/pubmed/24647281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092185
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