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Structural Dynamics of HIV-1 Envelope Gp120 Outer Domain with V3 Loop

BACKGROUND: The net charge of the hypervariable V3 loop on the HIV-1 envelope gp120 outer domain plays a key role in modulating viral phenotype. However, the molecular mechanisms underlying the modulation remain poorly understood. METHODOLOGY/PRINCIPAL FINDINGS: By combining computational and experi...

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Détails bibliographiques
Auteurs principaux: Yokoyama, Masaru, Naganawa, Satoshi, Yoshimura, Kazuhisa, Matsushita, Shuzo, Sato, Hironori
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356331/
https://ncbi.nlm.nih.gov/pubmed/22624045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037530
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