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Thymosin β(10) Expression Driven by the Human TERT Promoter Induces Ovarian Cancer-Specific Apoptosis through ROS Production

Thymosin β(10) (Tβ(10)) regulates actin dynamics as a cytoplasm G-actin sequestering protein. Previously, we have shown that Tβ(10) diminishes tumor growth, angiogenesis, and proliferation by disrupting actin and by inhibiting Ras. However, little is known about its mechanism of action and biologica...

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Detalhes bibliográficos
Main Authors: Kim, Young-Chae, Kim, Byoung-Gie, Lee, Je-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356296/
https://ncbi.nlm.nih.gov/pubmed/22623951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035399
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