An Analogue of the Antibiotic Teicoplanin Prevents Flavivirus Entry In Vitro

There is an urgent need for potent inhibitors of dengue virus (DENV) replication for the treatment and/or prophylaxis of infections with this virus. We here report on an aglycon analogue of the antibiotic teicoplanin (code name LCTA-949) that inhibits DENV-induced cytopathic effect (CPE) in a dose-d...

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Detalhes bibliográficos
Main Authors: De Burghgraeve, Tine, Kaptein, Suzanne J. F., Ayala-Nunez, Nilda V., Mondotte, Juan A., Pastorino, Boris, Printsevskaya, Svetlana S., de Lamballerie, Xavier, Jacobs, Michael, Preobrazhenskaya, Maria, Gamarnik, Andrea V., Smit, Jolanda M., Neyts, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356272/
https://ncbi.nlm.nih.gov/pubmed/22624001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037244
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