PLGA nanoparticle-mediated delivery of tumor antigenic peptides elicits effective immune responses

The peptide vaccine clinical trials encountered limited success because of difficulties associated with stability and delivery, resulting in inefficient antigen presentation and low response rates in patients with cancer. The purpose of this study was to develop a novel delivery approach for tumor a...

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Autors principals: Ma, Wenxue, Chen, Mingshui, Kaushal, Sharmeela, McElroy, Michele, Zhang, Yu, Ozkan, Cengiz, Bouvet, Michael, Kruse, Carol, Grotjahn, Douglas, Ichim, Thomas, Minev, Boris
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356185/
https://ncbi.nlm.nih.gov/pubmed/22619507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29506
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