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PLGA nanoparticle-mediated delivery of tumor antigenic peptides elicits effective immune responses

The peptide vaccine clinical trials encountered limited success because of difficulties associated with stability and delivery, resulting in inefficient antigen presentation and low response rates in patients with cancer. The purpose of this study was to develop a novel delivery approach for tumor a...

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Detalhes bibliográficos
Main Authors: Ma, Wenxue, Chen, Mingshui, Kaushal, Sharmeela, McElroy, Michele, Zhang, Yu, Ozkan, Cengiz, Bouvet, Michael, Kruse, Carol, Grotjahn, Douglas, Ichim, Thomas, Minev, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356185/
https://ncbi.nlm.nih.gov/pubmed/22619507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29506
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