Effects of a Fluorescent Myosin Light Chain Phosphatase Inhibitor on Prostate Cancer Cells

Myosin light chain phosphatase (MLCP) is an enzyme important to regulation of cell cycle and motility that is shown to be upregulated in aggressive prostate cancer cells and tissue. We developed a fluorescent small molecule inhibitor of MLCP using structure based design in recombinant protein phosph...

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Detalhes bibliográficos
Main Authors: Grindrod, Scott, Suy, Simeng, Fallen, Shannon, Eto, Masumi, Toretsky, Jeffrey, Brown, Milton L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356144/
https://ncbi.nlm.nih.gov/pubmed/22655237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2011.00027
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