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Phosphorylation-dependent Autoinhibition of Myosin Light Chain Phosphatase Accounts for Ca(2+) Sensitization Force of Smooth Muscle Contraction
The reversible regulation of myosin light chain phosphatase (MLCP) in response to agonist stimulation and cAMP/cGMP signals plays an important role in the regulation of smooth muscle (SM) tone. Here, we investigated the mechanism underlying the inhibition of MLCP induced by the phosphorylation of my...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755881/ https://ncbi.nlm.nih.gov/pubmed/19531490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019729 |
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