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The Insulin Receptor: A New Target for Cancer Therapy

A large body of evidences have shown that both the IGF-I receptor (IGF-IR) and the insulin receptor (IR) play a role in cancer development and progression. In particular, IR overactivation by IGF-II is common in cancer cells, especially in dedifferentiated/stem-like cells. In spite of these findings...

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Detalhes bibliográficos
Main Authors: Malaguarnera, Roberta, Belfiore, Antonino
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356071/
https://ncbi.nlm.nih.gov/pubmed/22654833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2011.00093
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