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Insulin-Like Growth Factor Binding Proteins: A Structural Perspective
Insulin-like growth factor binding proteins (IGFBP-1 to -6) bind insulin-like growth factors-I and -II (IGF-I and IGF-II) with high affinity. These binding proteins maintain IGFs in the circulation and direct them to target tissues, where they promote cell growth, proliferation, differentiation, and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356058/ https://ncbi.nlm.nih.gov/pubmed/22654863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2012.00038 |
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