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The Adaptor Protein Crk Controls Activation and Inhibition of Natural Killer Cells

Natural killer (NK) cell inhibitory receptors recruit tyrosine phosphatases to prevent activation, induce phosphorylation and dissociation of the small adaptor Crk from cytoskeleton scaffold complexes, and maintain NK cells in a state of responsiveness to subsequent activation events. How Crk contri...

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Hlavní autoři: Liu, Dongfang, Peterson, Mary E., Long, Eric O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355982/
https://ncbi.nlm.nih.gov/pubmed/22464172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.007
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