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Receptor Oligomerization in Family B1 of G-Protein-Coupled Receptors: Focus on BRET Investigations and the Link between GPCR Oligomerization and Binding Cooperativity

The superfamily of the seven transmembrane G-protein-coupled receptors (7TM/GPCRs) is the largest family of membrane-associated receptors. GPCRs are involved in the pathophysiology of numerous human diseases, and they constitute an estimated 30–40% of all drug targets. During the last two decades, G...

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Библиографические подробности
Главные авторы: Roed, Sarah Norklit, Orgaard, Anne, Jorgensen, Rasmus, Meyts, Pierre De
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Research Foundation 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355942/
https://ncbi.nlm.nih.gov/pubmed/22649424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2012.00062
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