Investigation of Prolactin Receptor Activation and Blockade Using Time-Resolved Fluorescence Resonance Energy Transfer

The prolactin receptor (PRLR) is emerging as a therapeutic target in oncology. Knowledge-based drug design led to the development of a pure PRLR antagonist (Del1-9-G129R-hPRL) that was recently shown to prevent PRL-induced mouse prostate tumorogenesis. In humans, the first gain-of-function mutation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tallet, Estelle, Fernandez, Isabelle, Zhang, Chi, Salsac, Marion, Gregor, Nathalie, Ayoub, Mohammed Akli, Pin, Jean Philippe, Trinquet, Eric, Goffin, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355858/
https://ncbi.nlm.nih.gov/pubmed/22649370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2011.00029
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados