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The glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates
The 300-kDa cation-independent mannose 6-phosphate receptor (CI-MPR) plays an essential role in the biogenesis of lysosomes by delivering newly synthesized lysosomal enzymes from the trans Golgi network to the endosomal system. The CI-MPR is expressed in most eukaryotes, with Saccharomyces cerevisia...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355666/ https://ncbi.nlm.nih.gov/pubmed/22369936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cws058 |
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