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Estrogen Regulates JNK1 Genomic Localization to Control Gene Expression and Cell Growth in Breast Cancer Cells

Steroid hormone and MAPK signaling pathways functionally intersect, but the molecular mechanisms of this cross talk are unclear. Here, we demonstrate a functional convergence of the estrogen and c-Jun N-terminal kinase 1 (JNK1) signaling pathways at the genomic level in breast cancer cells. We find...

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Detalhes bibliográficos
Main Authors: Sun, Miao, Isaacs, Gary D., Hah, Nasun, Heldring, Nina, Fogarty, Elizabeth A., Kraus, W. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355551/
https://ncbi.nlm.nih.gov/pubmed/22446103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1158
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